Injectables Overview: Toxins and Neuromodulators
Toxins or neuromodulators, such as Botox, Xeomin, Daxxify, and Jeaveau at Ali’i Nani Aesthetic Medicine, are effective treatments for moderate to severe frown lines and wrinkles. They work by relaxing dynamic expression lines, with results typically lasting between three to four months.
Our Approach
At Ali’i Nani Aesthetic Medicine, we prioritize a natural look. The best treatments are those where the changes are subtle and not easily identifiable. With our approach, you can look younger and more rejuvenated while looking natural.
Pre-Treatment Guidelines
To minimize the risk of bruising, we recommend avoiding the following seven days before your procedure: Aspirin, Ibuprofen, Motrin (or any other NSAIDs), fish oil, and Vitamin E. Additionally, refrain from consuming alcohol seven days before and after the procedure. Please try to avoid wearing makeup as much as possible.
Post-Treatment Guidelines
After your treatment, remain upright for the next few hours and avoid the gym for 24 hours. In case of bruising, you can apply an ice pack or topical arnica cream. Please refrain from facials for one week.
Treatment Duration
The duration of treatment depends on the number of areas being addressed. Typically, it takes under 10 minutes.
Injection Areas
Injectable treatments can be administered in various areas, including forehead lines, frown lines (the “11s”), crow’s feet (around the eyes), bunny lines (lines that form when you scrunch your nose), neck bands, a pebbled chin, a sad smile, lip lifts, and for excessive sweating (underarms and palms). We can also provide a brow lift to some extent.
Cost of Treatment
The cost of treatment varies among patients, as the number of units (dosing) depends on the assessed wrinkles during your appointment. Our providers will give you a quote on the day of your visit. Established patients can enjoy our VIP pricing or enjoy discounts when they participate in our premium membership.
Follow-Up Appointment
If you’re a new patient, we recommend a follow-up appointment after two weeks to evaluate your results. This allows us to make any necessary adjustments or add additional units if needed. We focus on avoiding over-treatment—the goal is to add more if required rather than overdoing it initially. Established patients typically do not return in two weeks but will schedule maintenance treatments every few months.
Best Age to Start Botox
While most clients begin botox treatments in their late 30s and older, we do have patients in their 20s who choose to start early to help prevent deeper wrinkles in the future. If wrinkles concern you, know that you have options.
Additional Wrinkle Prevention Tips
In addition to Botox, consider the following to prevent wrinkles: wear sunscreen daily, stop smoking and limit alcohol consumption, maintain a healthy diet, engage in regular exercise, use medical-grade skincare (check out our own line Ali’i Nani Skincare), and explore non-invasive treatments like lasers and radiofrequency microneedling, as well as our medical facials available at Ali’i Nani. All injectables are administered by licensed medical professionals at our med spa.



All injectables are administered by licensed medical professionals at our medspa. We use Botox, Xeomin, Daxxify and Jeaveau at Ali’i Nani Aesthetic Medicine. Dosed right, they last on average 3-4 months.







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This review is long overdue. Dr. Marie Williams and her team are beyond great! Mehana and Sadie are so welcoming and professional. I’ve been coming here for almost 3 years and if you review my before and after photos, Marie’s skilled techniques and assessments speak for itself. She is THE Injector and she slays. Age ain’t got nothing on her—I not only got the results I wanted but felt that it was worth the investment. Mahalo Nui to the entire Ali’i Nani Team! – DG
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